Antidepressant Usage, Stress And High-fat Diet Combo Linked To Long-term Weight Gain

Antidepressant Usage, Stress And High-fruitful Diet Combo Linked To Long-confine Weight Gain

Short-term users of antidepressants who are stressed and waste a high-fat diet might esteem a higher risk of long-confine weight gain, researchers from the Australian National University in Canberra, Australia, explained steady Sunday at The Endocrine Society's 95th Annual Meeting in San Francisco, California, USA.

Lead inventor Suhyun Lee, said:

"Our study suggests that sharp-term exposure to stress and antidepressants, rather than a high-calorie, high-stupid diet alone, leads to long-expression body weight gain, accompanied with increased bone and peevishness weights."

Hundreds of millions of antidepressant prescriptions are written each year globally. In the USA alone, prescriptions filled conducive to antidepressants rose from 154 million in 2002 to 170 the masses in 2005. In 2008, more than 12 the masses such prescriptions were filled in Australia.

In developed and emerging nations fleshiness rates are rising. Two-thirds of American and Australian adults are fleshy/overweight today. Obesity/overweight are expose to danger factors for a wide range of dangerous and chronic diseases, including heart infirmity, diabetes, some cancers, sleep apnea, etc.

Although antidepressants contribute assistance with depressive symptoms, they are furthermore associated with weight gain. How plenteous weight a patient might put adhering varies. Some have gained 7% in bodyweight from that time starting on their medication.

In this study, laboratory rats went from one side a two-week period of repeated suppression to induce stress, with one cluster receiving fluoxetine, an antidepressant, and the other a placebo salt-spring solution (the control group). Then, the couple groups received a high-fat diet as being 295 days.

Lee and team found that the stress-induced mice without interrupti fluoxetine gained much more weight than the govern animals (rats not on fluoxetine). The rats up the body fluoxetine also gained bone and ill-humor weight, compared to the controls.

Lee declared:

"These findings may implicate different pathophysiological mechanisms in force and antidepressant related obesity when compared to corpulence that is solely diet-induced."

The researchers in addition found that fluoxetine helped reduce symptoms of disquietude in the stress-induced rats.

In 2011, researchers from the University of Amsterdam, the Netherlands, demonstrated in a study that patients using antidepressants continuously were further overweight than intermittent or non-users.

Written by Christian Nordqvist
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